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4th Floor, HB Twin Tower NSP, Pitampura, New Delhi-34

H–482, Vikaspuri, Delhi OPD Only

Kalpataru Multispeciality Clinic, 225 DDA SFS, Sector-9 Pocket 1 Dwarka, New Delhi - 110075

South Ex Front Flat, 3rd Floor, N-5, South Extension-1, New Delhi - 110049

IVF Blog Detail

How to Prepare yourself for Blastocyst Transfer

No matter how things were before becoming parents, as we are all aware, relationships are frequently strained. With the aid of assisted reproductive technology (ART), such as in vitro fertilization (IVF), infertile intended parents can have children. We have come up with the best and easiest solution for you. I ensure after reading this blog all queries related to blastocyst transfer would be resolved.

What does “blastocyst transfer” signify?

Blastocyst transfer will be briefly defined before the direct question is addressed. Embryos can now be successfully cultured up to the blastocyst stage thanks to recent improvements in IVF lab procedures and culture material. Compared to embryos at an earlier stage, blastocysts might have a higher chance of implanting into the uterine wall. It’s likely due to an underlying issue that many embryos cease developing at the four to eight cell stage. Normal embryonic development stops at the eight-cell stage in any genetically defective embryos. There will be fewer embryos that can develop into a blastocyst as a result.

In vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) involves the development of a fertilized embryo for 5–6 days following the fusing of an egg and sperm (ICSI).

What does a blastocyst look like?

A blastocyst and a day three embryo seem extremely different under the microscope. The blastocoel, a cavity filled with fluid, is located in the centre. The inner cell mass, another region with a substantial number of cells, will give rise to the foetus. The placenta is created by a third collection of cells located close to the central cavity.

Now let’s quickly go over what happens following fertilisation in assisted reproductive technologies (ART). Eggs and sperms have 23 chromosomes each in a state known as haploid, but human cells normally have 46 chromosomes, or diploid, in this form. These haploid cells combine to create a diploid cell known as a zygote during fertilization using IVF or ICSI. This initiates the embryonic stage, which is followed by the embryo’s formation.

Embryonic stage constitutes the following:

  • Day 1 – Pronuclear stage (to check number of eggs fertilised by a sperm successfully)
  • Day 2 – Two- to four-celled stage (only successfully formed embryos)
  • Day 3 – Eight-celled stage
  • Day 4 – 16-celled stage called Morula
  • Day 5/6 – Blastocyst stage

At the four to eight cell stage, IVF embryos are typically transferred on the second or a third day following egg retrieval. The blastocyst transfer stage (100-150 cells) is when the IVF embryos must develop for two or three more days before they are prepared for implantation into the uterine wall (endometrium).

Blastocyst embryo transfer recommended for?

Blastocyst culture is being given as an alternative option to couples who have tried IVF or IVF-ICSI unsuccessfully despite having several high-quality eggs recovered. Couples that are strong candidates for blastocyst culture include those who have several healthy embryos on day 3. The likelihood of these couples becoming pregnant should increase with the capacity to choose the most healthy embryos for transfer and implantation.

How does transferring blastocysts benefit you?

A developing embryo generally exits the fallopian tube and enters the uterus at the blastocyst stage (five days after fertilisation). The blastocyst begins to implant itself to the uterus lining once it has reached the uterus, a practice called as implantation.

The benefit of trying to develop embryos to the blastocyst is that since this stage of development is more compatible with the uterine environment, it should increase the likelihood that the embryos will implant. Fewer embryos will need to be replaced as a result, lowering the possibility of having multiple pregnancies.

What are the risks involved in blastocyst transfer?

The drawback is that very few embryos (probably between 30% and 50% of them) will “survive” or develop to this stage. A 10% chance exists that no embryos will develop to the blastocyst transfer stage, leaving no embryos eligible for transfer. There are also a lot fewer “spare” embryos available for freezing.

You should speak with your specialist about the potential increase in conception that this form of treatment may produce. It depends on the woman’s age, diagnosis, and partner’s initial semen analysis.

The Final Outcome

Here comes the problem: where will you get the best blastocyst transfer surgery? But don’t worry, our IVF expert Dr. Rashmi Sharma will take excellent care of you. If you want to have a word with her, schedule an appointment with the best IVF Center in Delhi just by making one phone call at 8080809084 or send your enquiry via an email at info@origynivf.com.


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