4th Floor, HB Twin Tower
NSP, Pitampura, New Delhi-34
H–482, Vikaspuri,
Delhi OPD Only
Kalpataru Multispeciality Clinic,
225 DDA SFS, Sector-9 Pocket 1 Dwarka,
New Delhi - 110075
South Ex Front Flat,
3rd Floor, N-5, South Extension-1,
New Delhi - 110049



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4th Floor, HB Twin Tower NSP, Pitampura, New Delhi-34

H–482, Vikaspuri, Delhi OPD Only

Kalpataru Multispeciality Clinic, 225 DDA SFS, Sector-9 Pocket 1 Dwarka, New Delhi - 110075

South Ex Front Flat, 3rd Floor, N-5, South Extension-1, New Delhi - 110049

IVF Blog Detail

Failed IVF Cycle: What To Do After First Failed IVF Cycle?

Achieving things the hard way will always be helpful as you will be deeply connected to the value of achieving that. This is not some random thought but an actual fact stated by many people who have achieved great heights in their life. At Origyn IVF, we understand that setbacks can be hard and thus, we have a team of the best IVF specialists who are there for you throughout your journey till you have your newborn in your arms. Being one of the best IVF centres in Delhi, it’s our duty to guide you about a failed IVF cycle and today, our IVF experts will share their guidance on what to do after the first failed IVF cycle.

The first and foremost thing is to not lose hope, we understand that it is easier said than done but, you must remain strong and prepare yourself mentally. You need to take some time and let your body and mind cope. If you choose the best IVF specialist for your IVF treatment, they will guide you from the very beginning, that you should not rely completely on your first IVF cycle as the chances of conceiving a baby in the first cycle are only 50%-60%.

The best practice that should be followed by every IVF expert is to analyze the reports and results of the IVF treatment by analyzing the results of the ovarian stimulation, fertilization and checking if there was any problem.  Once they find out the actual issue they should contact the couple and share this with them and guide them on how this can be avoided or the impact can be reduced in the future IVF cycle. Our IVF experts believe in setting up the right expectations and following the best practice, let us share some of the common reasons for IVF failure.

Reasons For IVF Failure-

Embryo Quality

During the laboratory portion of IVF treatment, the female’s eggs and the male’s sperm are mixed together with the aim of creating an embryo. Embryos can appear healthy in the lab, but when implanted into the uterus there is a possibility that they fail to implant due to an invisible defect.

The embryos that are ultimately transferred into the woman’s uterus are selected by the embryologist. Unfortunately, our ability to distinguish chromosomally normal from chromosomally abnormal embryos remains severely limited. Essentially, our IVF specialists select embryos for transfer based on three basic criteria-

Cell Stage
Embryo Grade
Rate of Cell Division

We know from studies performed in our laboratory that on day three, embryos that have developed to at least the 8 cell stage have a much better prognosis for success than embryos that have 5 or fewer cells.

Similarly, our IVF experts that embryos that are of a better grade (Grade A)  are much more likely to implant than those embryos with lower grades (Grade B or Grade C). In addition, as we observe the embryos on a regular basis, our embryologists are able to determine the rate of cell division. For example, an embryo that gradually reaches the 8 cell stage by day three is much more likely to do well than an embryo that has delayed fertilization and rapid growth towards the end of this time period.

Role of Maternal Age in IVF Success

One of the most important reasons for IVF failure is maternal age, the higher the mother’s age, the lower the IVF success rate. Investigations have revealed that the success rate of IVF for 35-year-old women is about 32%, while this number decreases to 16% for women over the age of 40.

In general, as the age of women increases, their ovarian reserve and their body’s response to ovarian induction drugs decreases. Eggs retrieved from women over 40 are of low quality, as a result, the resulting embryos have a low grade. Moreover, women over 35 may face chromosomal disorders in the embryo, failure in the implantation and abortion.

Uterine Factors

A healthy uterus is one of the most important factors of a successful IVF treatment. In the case of IVF failure, the IVF specialist carefully examines the uterus using hysteroscopy to rule out any polyp or septum that may cause hindrance in the implantation of the embryo. In the hysteroscopy method, a special narrow camera called a hysteroscope is used to examine all parts of the uterus. If there is any obstacle or problem in the female reproductive organs, then, the IVF expert resolves it then, and there.

Lifestyle Factors

At Origyn IVF, we make it very clear that your lifestyle will play one of the most important roles in the success of your IVF cycle. This has been seen in many cases where factors like smoking, an imbalanced diet, and being under or overweight have impacted the IVF cycle and resulted negatively.

Some of the other factors that may cause low endometrial receptivity and may be the reason for IVF failure are –

  • Thin Endometrial Tissues
  • Uterine Fibroids
  • Septate Uterus
  • Intrauterine Adhesions (IUAs)
  • Uterus Infection
  • Hydrosalpinx
  • Endometriosis, etc.

Future Steps

Once you are aware of what can lead to an IVF failure, you should also be aware of your future options. You should always take your time in order to understand the situation and then, choose whether you want to proceed or not. But, you should not give up on your dream of having your own baby as there are numerous options available for you, some of these are –

Another IVF Cycle

We can understand that opting for the same option again can be hard as there will be doubts in your head however, you should only go through it if your IVF specialist can clearly state the cause of IVF failure and explain how it can be resolved in the 2nd IVF cycle. If you gain clarity and you can trust the IVF expert, then, going for another IVF cycle can be truly fruitful.

Opting For Surrogacy

Many women face trouble in carrying out the embryo and for them, surrogacy is a great option as the baby is not genetically related to the surrogate and will be having your genes and characteristics. You should always look for healthy and legitimate surrogates and make sure that they go through medical and psychological examinations before the procedure.

Third-Party Donor

This is a very good and successful option for women who are above 35 and have poor quality or quantity of eggs. They can opt for choosing a 3rd party egg donor and before proceeding you should get the donor clinical checked and look for someone who is less than 30.

As we stated at the start, we understand that setbacks and failure are hard to deal but having the right guidance and support can help you eventually achieve your dream. The dream of having a baby and completing your family is not a dream which you can give up easily. It will have some obstacles but with the help of Origyn IVF, one of the best IVF centre in Delhi, you will surely be able to fulfil this beautiful dream. Book your free consultation today or call us at 08080809084.


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